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There is not enough information in the question to directly answer it.

If the question meant to say "Can two people with RH+ and RH- blood type have children?" the answer is twofold...

If the mother is RH+ and the father is RH-, there will be no problem.

If, however, the mother is RH- and the father is RH+, then the mother's body will attempt to reject the fetus. This is often not a problem for the first child, but it is a life threatening problem for the second and subsequent child, because the mother's body remembers the "foreign organism", and is better prepared to fight it the second time.

If the doctors know about the RH incompatibility in advance, then they can often treat the mother to help reduce the chance of problem.

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Q: Can a positive and a negative have children together?
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