Yes, ibuprofen and most "NSAIDS (non-steroidal anti-inflammatory agents) like naproxen can be taken with the majority of antihypertensive agents, though some nephrologists feel that they should be avoided or only used occasionally along with "ACE-inhibitor" blood pressure medications like Capoten, Altace, Cozaar, Zestril due to their having a similar pathway of excretion from the body.