Tramadol is a weak opioid and a weak SSRI. Ibuprofen is an NSAID. There exists no significant interactions between the two drugs. However, since tramadol does indeed have some SSRI properties, and to...
Well, I just did. I'll let you know if I survive. (Not a joke). In all likelihood, low doses of both should be okay. Ibuprofen is a pain reliever and reduces inflammation. Pain relieves are not good...