Can you take acetaminophen and tramadol together?

Answer 1

Yes. They are two different compounds that work well together.

So well that some formulations of tramadol contain acetaminophen already, going under the brand name Ultracet. So make sure you read the label before you add more acetaminphen/Tylenol (or even take Nyquil). If you see tramadol + APAP, this means you have that generic formulation. Acetaminophen can do severe liver damage (to the point of killing you). It has a daily limit of 4000mg. 3000mg if you are going to be using it every day.

Tramadol is a special kind of opiate, where it works both like morphine and also on serotonin receptions. Therefore, there IS a daily limit, and it can potentially interact with SSRI/SNRI medications, as well as the tripan migraine medications (which also work on serotonin receptors). Supplements such as St. John's Wort work on serotonin receptors as well. It is important to make sure your prescribing physician knows everything you are taking and to follow the prescribing advice on how much to take.

Answer 2

If you are treating Arthritis pain, tramadol is good enough to give you immediate relief. It is not advisable that you combine tramadol with another pain reliever since it can magnify potential side effects.

Answer 3

tramadol and acetaminophen are actually made in a combination product in the US. there is no adverse reaction between the two medications, but there is an upper limit on the amount of acetaminophen that can safely be taken per day ( 3 grams per current FDA labeling requirements).