I can only answer anecdotally. It appears that Wellbutrin & Zyrtec do react when used together. When my Wellbutrin got up'd to 300mg (I also take 100mg of Zoloft), the Zyrtec made me incredibly...
No, it is not recommended. Wellbutrin (bupropion) and Vyvanse (lisdexamfetamine) are dangerous if taken together because this combination has been known to cause seizures (which can be fatal if not...