Well, a typical "he" will be male. In human, this means that "he" will produce hormone testosterone and not estrogen which is what "she" will produce. Also, "he" will not have a mammary glands...
If you mean Alfredo as in Alfredo pasta sauce, he was Italian chef, restaurateur and innkeeper. At his restaurant Alfredo alla Scrofa in Rome, he famously served his fettuccine Alfredo pasta dish, to...