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Can elevated serum ketone levels elevate the blood alcohol concentration levels?
Wiki User
∙ 7y ago
One reference to J Forensic Sci. 1995 Jul;40(4):686-7.
states:
We report the identification of acetone (0.45mg/mL) and isopropanol (0.17 mg/mL) but without the presence of ethanolin a blood sample from a man suspected of driving under the influenceof alcohol. A preliminary breath screening test with an electrochemicalinstrument (Alcolmeter S-L2) was positive and an evidential breath-testwith a dual wavelength infrared analyzer (Intoxilyzer 5000), recognizedthe presence of an interferant in the subject's breath. The manadmitted drinking moderate amounts of alcohol (vodka) the previousevening and was being treated by his doctor for hyperglycemia byspecial dietary control. This case scenario provides a good example ofsevere metabolic ketoacidosis in an ostensibly healthy man driving on the highway. Biotransformation of the abnormally high concentration ofblood-acetone to isopropanol occurs through the alcohol dehydrogenasepathway.
PMID: 7595310 [PubMed - indexed for MEDLINE]
Another reference (more recent) is even more interesting as it relates to to a person on a low carb high fat diet (like Atkins).
Int J Obes (Lond). 2007 Mar;31(3):559-61. Epub 2006 Aug 8
A 59-year-old man undergoing weight loss with verylow calorie diets (VLCD) attempted to drive a car, which was fittedwith an alcohol ignition interlock device, but the vehicle failed tostart. Because the man was a teetotaller, he was surprised and upset bythis result. VLCD treatment leads to ketonemia with high concentrationsof acetone, acetoacetate and beta-hydroxybutyrate in the blood. Theinterlock device determines alcohol (ethanol) in breath byelectrochemical oxidation, but acetone does not undergo oxidation withthis detector. However, under certain circumstances acetone is reducedin the body to isopropanol by hepatic alcohol dehydrogenase (ADH). Theignition interlock device responds to other alcohols (e.g. methanol,n-propanol and isopropanol), which therefore explains thefalse-positive result. This 'side effect' of ketogenic diets needsfurther discussion by authorities when people engaged insafety-sensitive work (e.g. bus drivers and airline pilots) submit torandom breath-alcohol tests.
PMID: 16894360 [PubMed - indexed for MEDLINE]
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Not likely. Ethanol in blood tests is usually determined enzymatically, with alcohol dehydrogenase. Interference from other alcohol type or ketones is usually considered to be less than 1%.
Wiki User
∙ 11y ago
Wiki User
∙ 7y agoYes, it can, if your a diabetic or on a fast. I've been doing the research. I had been fasting for 3 days and one glass of wine and blew a .184, I should of been drunk but was completely sober.
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What is the result when you reduce a ketone?
A Secondary Alcohol When reduced with something like lithium aluminum hydride, a ketone results in a secondary alcohol.
What is the secondary alcohols are oxidized?
Mild oxidation of a secondary alcohol will produce a ketone; strong oxidation, such as burning, can produce carbon dioxide and water.
What is the product when secondary alcohol is oxidized?
ketone
How is a ketone differerent from an alcohol?
A ketone is a R-C(=O)-R bond, not to be confused with an aldehyde R-CHO. An alcohol is an R-C-OH group.
What classification of alcohol undergoes oxidation to yield a ketone?
A secondary alcohol undergoes oxidation to yield a ketone; a primary alcohol forms an aldehyde instead, and a tertiary alcohol usually does not form either a ketone or an alcohol, because the carbon having the OH group in a tertiary alcohol already has three bonds to other carbon atoms and therefore cannot form a double bond to oxygen without more extensive breaking of other bonds in the tertiary alcohol.
Which alcohol contains four carbon atoms and can be oxidised to a ketone?
Butanol
What is the oxidation of alcohol?
Oxidation of a primary alcohol results in an Aldahyde, 2 molecules of primary alcohol oxidized results in an ether, oxidization of a secondary alcohol end product is a ketone. Oxidation of a primary alcohol results in an Aldahyde, 2 molecules of primary alcohol oxidized results in an ether, oxidization of a secondary alcohol end product is a ketone.
Undesirably high concentration of ketone bodies in the blood and urine?
Condition known as Ketosis
What is Ketonemia defined as?
Ketonemia is defined as the presence of abnormal ketone bodies at an elevated level. Another name for ketonemia is hyperketonemia.
What product contains carboxylic acid?
reducing a carboxylic acid directly forms an aldehyde, but further reduction forms a primary alcohol reducing a ketone forms a secondary alcohol oxidation reverses these processes primary alcohol -> aldehyde -> carboxylic acid secondary alcohol -> ketone
Which functional groups are present in carbohydrates?
alcohol, aldehyde, or ketone.
What functional group can you get after the oxidation of a hydroxyl group?
if the alcohol is a primary alcohol the itis oxidized to give aldehyde and if secondary it gives ketone.
