Katherine Hepburn never had any children. She was married to Ludlow Ogden Smith from December 1928 to May 1934 when they become divorced.
No, she never gave birth too or adopted children.
any of the children have
Yes he has three Jak-jak, hershy, and blaridine levere.
Nope, no relation. Kate did have an actress niece, Katharine Houghton, and they appeared in Guess Who's Coming To Dinner together.