Properties Endotoxin Exotoxin
Chemical nature Lipopolysaccharide protein
Mol Weight 10 kDa 50-1000 kDa
Relationship to cell Part of outer membrane Extracellular
Heat effect Not denatured Denatured
Can be toxoided No Yes
Specificity Low High
Pyrogenicity Yes Occasional
Produced by G-ve bacteria G+ve bacteria
Antigenicity Poor Good