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The main test to distinguish strep spp. from staph spp. is the catalase test. Staph spp. are catalase + whereas strep spp. are catalase -.

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There are numerous test that are used to differentiate streptococci from Staphylococci. Just to name a few:

Although they are both Gram Positive, their morphology (structures) are obviously different. Under a microscope strep usually looks like a chain of cocci while staph looks like a cluster of grapes formation.

Lab test will show obvious differences in their hemolytic activity. For example, test will show the presence of leukocidin and staphylokinase (substances that are specific to staph bacteria).

Test will also show suscetability of staph bacteria to the antimicrobial agent Novobiocin. Test will aslo show staph reaction to carbohydrate mannitol.

There are many other test that will differentiate the two bacteria, this was just to name a few.

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12y ago
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11y ago

Both are Gram positive and have the similar spherical cell shape, but the arrangement of cells is different due to a different binary fission. Streptococci form a chain of round cells, because their division occurs in one linear direction, whereas staphylococci divide in various directions forming grape-like clusters.

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what is the difference between lactobacillus and lactococcus

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Q: Differentiate the microscopic morphology of staphylococci and streptococci as seen by gram stain?
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