Hey I you want to play Sega Saturn games on your PC there are a few programs out there that make this possible, I have recently wrote a blog post on this subject, creating a tutorial to help people...
No, you cannot !Directly from the Sega Saturn manual:"You cannot use Genesis, Sega CD, or Genesis 32X games or peripheral equipment with your Sega Saturn."
Yes you can play Sega Saturn games on your PC. Check out this blog I wrote on the subject, this will show you exactly how to get you favourite classics working on your PC....