The shortest route is I-80W. The drive takes 1hr 4 min. The distance is 58 miles.
15.83 kilometres (9.84 miles)
28 miles taking this route: Follow signs to the EXIT and I-5 from the airport. Once you are at I-5, follow signs to I-5 SOUTH to SACRAMENTO. Take I-5 SOUTH to I-80 EAST to RENO at EXIT 522. Take I-80...
81.74 kilometres (50.79 miles) and 165.35 kilometres (102.74 miles)
~64 miles to the center of Napa Valley