In the movie , it's New Goblin , Sandman , and Venom . In the game , it's this one robot guy , Morbius , Shriek , Lizard , Mega Lizard (looks scary but awesome) , Venom , Sandman , Giant Sandman ,...
Adrian Toomes A.K.A. the Vulture played by John Malkovich until "Spider-Man 4" was cancelled due to Sam Raimi refusing to negotiate with the producers over what the story would actually be.
Nobody because there is not going to even be a "Spider-Man 4". But there is going to be a reboot called "The Amazing Spider-Man" and he is supposed to be fighting the Lizard (Dr. Curt Connors...