Does Captopril causes hypokalemia or hyperkalemia?

Answer:
Hyperkalemia. Captopril is an ACE (angiotensin converting enzyme) inhibitor which has various actions on the cardiovascular and renal systems. One of these actions in inhibition of the formation of Angiotensin II and aldosterone. Aldosterone acts to increase sodium (and water) reabsoprtion in the collecting duct of the nephron. In this process potassium is excreted. If aldosterone release is inhibited by Captopril then sodium reabsorption is decreased and potassium remains in the blood, leading to hyperkalemia.
First answer by ID1147766566. Last edit by Pengland02. Contributor trust: 0 [recommend contributor recommended]. Question popularity: 1 [recommend question].