As an anhydride, It can be prepared by dehydrating its acid, i.e. Acetic acid, by strong dessicant such as Tetraphosphorus decaoxide (P4O10) : P4O10 + 12 CH3COOH ----> 4 H3PO4 + 6 (CH3CO)2O
Yes it think they will react, if Acetic acid is hot and concentrated, and iron is in form of steel wool. It will produce Iron(III) acetate and hydrogen, and left over will be small amount of carbon....