Answer:
No it does not. Tylenol damages the liver, so many oxycodone preparations WILL damage the liver. For example, percocets are a combo of oxycodone and Tylenol. Those can cause liver damage because of the Tylenol. But drugs that are single-entity opiods and have no Tylenol (like Oxycontin or Roxicodone) do not damage the liver. It is just the Tylenol to be honest.