How are Down syndrome and Klinefelter syndrome genetically similar?

Answer:
Both syndrome's indicate the presence of a 47th chromosome (or extra part of a chromosome). Most humans have 23 pairs of chromosomes, totaling 46 chromosomes.

For Down's syndrome, the 47th chromosome appears with the 21st pairing. For Klinefelter's syndrome the 47th chromosome appears with the 26th pairing (the gender chromosomes.)
First answer by Jkmyoung. Last edit by Jkmyoung. Contributor trust: 413 [recommend contributor recommended]. Question popularity: 1 [recommend question].