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How are belladonna alkaloids used as a medication?

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Answer

The mostly widely used alkaloid from Atropa belladonna plants is atropine, which is a tropane alkaloid.

Some of its uses include:

Antidote to the toxic effects of cholinesterase inhibitors since it is a known anticholinergic, and therefore, prevents the toxic effects that can result due to accumulation of acetylcholine in the neuromuscular junctions and the parasympathetic nervous system.

Sometimes used by optometrists and opthalmologists as a cycloplegic, which paralyzes the accommodation reflex and thus induces mydriasis (pupil dilation) during eye examination.

Several belladonna alkaloids as well are used in combination with phenobarbital to relieve cramping pains, in cases such as irritable bowel syndrome

First answer by Zero9001. Last edit by Zero9001. Contributor trust: 164 [recommend contributor ]. Question popularity: 32 [recommend question].

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