How are diseases inherited caused by a single gene?

Answer:
It only takes one mutated gene to cause a genetic disease. For example, in sickle cell anemia, a single misplaced base pair on a gene causes a protein in red blood cells to become malformed. As a result, the blood cells are sickle shaped and no longer function as they should. Just that one point mutation in that one protein caused a serious problem in individuals with that gene.
First answer by Blue. Last edit by Blue. Contributor trust: 2481 [recommend contributor recommended]. Question popularity: 2 [recommend question].