Answer:
The length of proteins vary from under 100 amino acids to many hundreds. The combination of 20 amino acids over a range of say 400 is enormous ie 400x399x398x397.....x1. It is not just the amino acids in a protein that determine the protein structure and function but also the order, which is responsible for interactions formed during the folding of the protein from a single long chain to its 3D structure. A single amino acid change in a protein of 400 amino acids can change the protein conformation.