Answer:
The key difference between a DNA nucleotide and an RNA nucleotide is their five-carbon sugar molecules.
One component of RNA is the five-carbon sugar ribose, C5H10O5. Alternatively, in DNA, the five-carbon sugar deoxyribose (C5H10O4) has one fewer oxygen atom.
Another difference is in the nitrogenous bases of some DNA and RNA nucleotides. The nitrogenous base uracil (U) is unique to RNA nucleotides. Similarly, the nitrogenous base thymine (T) is unique to DNA nucleotides.