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This has always been a problem for Duragesic users like myself, particularly during the Summer months. However, there are several ways you can help keep your patch(es) in place:

1. If you're using Duragesic and not the generic patches (most people like me who've used Duragesic for years can't use them), Janssen Pharmaceuticals, the maker of the patch, has a program for users of their patch to deal with the problem. Qualified individuals are sent a package of Bioclusive cover bandages to place over the existing patch. Bioclusives are transparent bandages that work like any other, but are just transparent and have different properties. The Bioclusive is large enough to fit over a single 100mcg patch and hold it in place. The information is in the Duragesic box, or you can call them directly at the number on the back of the box. The Bioclusive program is one of the menu items. Note that it is ONLY for Duragesic users; if you're using the generic patch, you're not qualified for the program.

2. Skin Prep - Skin Prep is a medical adhesive skin preparation, normally used by Colostomy patients who have much greater adhesive/adhesion requirements. Skin Prep preps the skin by adding a thin layer of a chemical that increases the adhesion of whatever it's stuck to. The key to using this though is that you must be absolutely precise in its application where the adhesive edges of the patch are to go. If careless, you can block the skin area where the patch membrane is when you apply your patch, thus preventing a full skin area for drug release.

There are 2 versions of the drug; one stings, the other is a 'non-sting" version. But the stuff works.

3. Medical/Surgical tape - You can use medical tape on the edges also. If the patch has come off, don't toss it if it's still intact and not stuck to itself. Clean the area where it was thoroughly, then put the patch back on using tape on the edges to hold it in place. Once removed from the skin, the patch adhesive is no longer strong enough to hold it in place on its own, so it needs tape or something like a Bioclusive patch to hold it. It takes a bit of time, but if you've got enough Fentanyl left in the patch, it'll start transferring within an hour or more depending on your body heat.

Having said that, at times requiring 2 100mcg patches myself every 48 hours (I'm in a small percentage of the population that only gets 48 hours out of the patch) I eventually figured out that the best way to keep them from coming off while sweating was to ensure they were put on properly in the first place. The only way to do this is to remove all skin oils from the area where the patch is going to be.

Ah, you say - but the directions say not to use alcohol for skin preparation, right? Actually, yes and no - the directions say not to use alcohol and THEN apply the patch. The reason for this is that Isopropyl Alcohol leaves a residue that can block drug release. So how do you get around this problem?

The answer is to use Isopropyl to clean the skin area, the to rinse/flush the area with water afterward to remove any residue left by the alcohol. Be sure not to use any soaps either, as they leave residue also.

Having used 1 or 2 100mcg Fentanyl patches for over 10 years now, I've always used them on my biceps, since for me they're the best place which affords the least skin flexing. Where you place your patch has a major effect on its adhesive capability as well. Any patch must be placed above the waist; many cancer patients I've known who've used them prior to passing on had them placed on the back. Anywhere you place the patch is supposed to be free of any body hair, as even small hairs can interfere with the patch. I've use mine for so long in the same place on both arms that hair doesn't grow there anymore, but when first starting I had to shave the areas where I put the patches. If you're wondering, I switch arms every time I switch change patches. You must give the area where you place your patch enough time to breathe and replenish itself.

I also offer this advice to any Fentanyl Patch user; as Schedule 2 opiate patients, all of us know the extreme restrictions placed on us by Federal Law, including the "minor problem" of only being given 30 days worth of medicine, only to lose one or more to sweating. I learned many years ago to maintain at least a 30 day emergency supply of all of my opiate medications, both primary and breakthrough (120/150 Percocet 10/325's per month). It is not easy to save up that much - if you have a good relationship with your Pain Specialist, you can always ask for extra, but be absolutely honest in why you're asking for it. Having had more bad doctors than good, it took a long time for me to find a good Pain Specialist, so be sure you've got a good one before saying anything if you should choose to try and bank extras for emergencies.

In my case, I used my breakthrough meds to substitute for my patches on those days when my pain wasn't as bad. It typically takes me a year to save that much - I've always kept my doctor informed, and he in turn has always given me a little extra in my prescription when my emergency supply ran low due to problems with my HMO or some other stupid reason. But I had the same doctor for 9 years, and I was one of his best patients. Never break the trust between you and your Pain Doctor - ever.

Those who have specific or further questions concerning patch adhesion may email me at the address at the top of my Supervisor Bio page.

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10y ago
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13y ago

to prevent fentynal patches from falling off you can cover them with Tagaderm adhesive patches, two for the smaller Tagaderm and 1 for the larger tagaderm. It works great but you might get some very annoying skin irritations.

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Q: How can you keep Duragesic Fentanyl Transdermal Patches from falling off when sweating?
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What are tansdermal Fentanyl patches?

Transdermal fentanyl patches (Duragesic) are a common example of a long-acting opioid drug often used for cancer pain management.


Who is the maker of fentanyl?

The oral drug Fentanyl is made by many different companies, but Duragesic (brand name for Fentanyl Transdermal patches) is made and distributed by Ortho-McNeil/Janssen Pharmaceuticals.


Fentanyl patches what is the brand name?

Duragesic transdermal system. Manufactured by Janssen-Cilag and available in 12, 25, 50, 75 and 100 micrograms/hour strength.


What are the strongest opiates that can be self administered?

Duragesic Patches (Fentanyl Transdermal patches) and either Demerol, Percocet, MS Contin, Morphine, and other similar Schedule 2 opiates. I personally use Duragesic, Percocet, Demerol and MS Contin, and have for almost 9 years.


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"Transdermal" means "through the skin". These cannot be injected.


Do Fentanyl patches contain caffeine?

No - they only contain Fentanyl in a transdermal release suspension gel.


Can you get Duragesic patches over the counter?

No. Duragesic (fentanyl) is a narcotic controlled substance that, in the US, is only available by prescription.


Is there help paying for Fentanyl patches?

Duragesic patches do - you can get a $50 coupon for your prescription from the Duragesic site, and they often include them in the boxes. For me it's enough to take care of my copay.


Is the Fentanyl transdermal system Duragesic dangerous and withdraw by the FDA?

No, the Fentanyl transdermal system (Duragesic) is not dangerous in and of itself. However, it is a potent opioid medication that can be harmful if not used appropriately or if misused. The FDA has not withdrawn Duragesic, but they have issued warning labels and safety information regarding its use to minimize the risk of misuse and accidental overdose.


Are there any contraindications for taking Dilaudid and Fentanyl transdermal patch together?

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Why were the Fentanyl patches recalled twice than put on the market?

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A patch containing the drug is applied to the skin and continues to deliver the drug to the person for typically three days.