How colchicine might effect daughter cells produced by a cell during mitosis?

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Colcichine inhibits the formation of spindle fibres during early metaphase.Thus the cell division process stops during late prophase.micotubule has 2 ends.+ end or - end.in microtubule growth addition of tubulins(subunit of microtubule) is much faster than removal of it at - end.but if we supply cochicine to the cells,new tubulins will form complexes with colchicine and when these tubulins added to + end,further elongation is inhibited,but removal of tubulins at the other end is still continuing,so we speak about degradation of mcrotubule.the end result is division process stopped,because now,metaphase is not possible.

First answer by Encikcipan. Last edit by Encikcipan. Contributor trust: 1 [recommend contributor]. Question popularity: 13 [recommend question]

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