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How deadly is primary lateral sclerosis?

In: Health, Conditions and Diseases, Osteoarthritis [Edit categories]

Answer:

PLS is not fatal, and people with the disorder can usually maintain mobility with the use of canes or other assistance.

First answer by Gale Ency of Neuro Dis. Last edit by Gale Ency of Neuro Dis. Contributor trust: 14 [recommend contributor ]. Question popularity: 2 [recommend question].

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What is primary lateral sclerosis?
a rare disease that causes progressive weakness in voluntary muscles such as in the legs, hands, and tongue. PLS is one of the diseases, along with amyotrophic lateral sclerosis, that are grouped...
How is primary lateral sclerosis diagnosed?
Diagnosis is based on the observance of the muscle weakness and the progressive worsening of the weakness. The diagnosis can be delayed because the disease is mistaken for ALS.
What causes primary lateral sclerosis?
Motor neuron diseases like primary lateral sclerosis develop because the nerve cells that normally control the movement of voluntary muscles degenerate and die.
How common is primary lateral sclerosis?
ALS is known to affect two to three people per 100,000. Tentative estimates of the occurrence of PLS are on the order of one person in 10 million
What neurons are affected in primary lateral sclerosis?
PLS affects a part of the neuron called the cell body (or soma). Specifically, it is the cell bodies of upper motor neurons that are affected.