Herman Cortes was the leader of the Spanish Conquest.
Peru: Francisco Pizarro. In Mexico: Hernan Cortes
The direct or indirect slaughter of millions of Native Americans due to slavery, forced removal or contagion from several diseases they weren't immune to, such as smallpox. It is stated that from an...
1519 - 1521.
Charles V was king of Spain in 1519 when Cortes conquered Mexico. See reference below: http://en.wikipedia.org/wiki/Hernan_Cortez#Conquest_of_Mexico