He sequestered himself away from all people except his doctor, who kept small fires burning around the Pope's desk while he read and signed letters etc. The smoke from the constantly burning fires may have kept the rats and their fleas away.
The Pope sat in a chair for 3 weeks surronded by fire to prevent the `bad air' coming to him. But it actually prevented rats or fleas coming to him.
Be good. Try to avoid being bad and no plague will come to you.
Pope Clement VI did live after the plague (Black Death 1348-1350). He died in 1352, two years after the plague.
Plague vaccine or avoid rats with fleas.
We don't hear about the plague as an outbreak. That is because modern antibiotics keep the plague at check.
run away
Pope did not know the reason. Doctors also did not know the reason or cure.
Avoid living in the Middle Ages Keep a clean house (free of fleas) and do not associate with people suspected of having the Plague.
Don't wear any clothing last worn by a plague victim.
Pope Clement VI
Pope Clement VI granted remission of sin to all who died of the Plague.
Counted deaths by Pope ClementVI was about 23,840,000.
The Black Death was an outbreak of plague that killed a third to half the people in Europe during the period of 1347 to 1352. At the time there was very little anyone could do to avoid it. I have read that some walled towns in England brought in food, raised their drawbridges, and waited until it passed, with some success, but I cannot provide a reference for this. Today, the bubonic plague can be treated with modern medicine.