How do antiepileptic drugs affect the skin?

Answer:
Certain antiepileptic drugs (AEDs) do affect the skin. For example, some people on carbamazepine (Tegretol) develop skin rashes with excessive sun exposure. With regard to lamotrigine (Lamictal), a very small percentage of individuals develop a rash (usually within the first week of use) that can be serious if the medication is not immediately discontinued (e.g. Stevens-Johnson Syndrome). There are others that can affect the skin, as well.
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