Action potentials also known as spikes, differ from graded potentials in that they do not deminish in strength as they travel through the neuron.
depolarization
It affects Action potential, as it basically paralyses anybody affected. To find out more, you can go to: http://www.mssociety.org.uk/about_ms/index.html .
The membrane potential must depolarize from the resting voltage of -70 mV to a threshold value of -55 mV.
A nerve is crushed between the two recording electrodes.