Lower division classes are broader "basic" courses commonly in the form of prerequisites for a major or minor. Passing these classes is typically required to be permitted to enroll into upper division classes, which are more specific to a major or minor.
For example, a Psychology 1 course at UC Berkeley is a lower division class that is required for majoring in Psychology, with its focus on the general basics of psychology. Passing Psychology 1 is required for enrollment into an upper division Psychology course such as Psychology 130 (Clinical Psychology), in which the material is much more focused and specific.
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