Answer:
My dad used to put an aspirin in a spoon with water and let it dissolve before I would ingest it.
The best way to dissolve aspirin is in a mortar and pestle. And then dissolve the powder in a glass of water before you drink it. The next best way is to chew it up real good in your mouth with your teeth, and then take a gulp of water and slosh it around in your mouth to dissolve the powdered aspirin. And then, swallow it all down with a full glass of water.