How do you fix a random multiple cylinder misfire detection on a 2002 Chevy 6.0liter?

Answer:
More then likely you have some bad spark plugs are plug wires.
I have seen the coils that are on top of the valve covers cause it too.
You really need to have the engine scanned with a engine scanner to locate the problem. It could be any of the 8 cyclinders.
First answer by Neutz. Last edit by Neutz. Contributor trust: 133 [recommend contributor recommended]. Question popularity: 3 [recommend question].