Itchy from Itchy & Scratchy in the Simpsons is a cartoon mouse.
Every day you replace your skin. When old skin is bothering you, you automatically want to get it of.
Normally, just scratch it. If it persists or if it turns red, bleeds, or forms a blister, apply calamine lotion and see a doctor.
Aloe vera gel seems to help me alot.
Because it has taste buds.