Hey I you want to play Sega Saturn games on your PC there are a few programs out there that make this possible, I have recently wrote a blog post on this subject, creating a tutorial to help people...
Yes you can play Sega Saturn games on your PC. Check out this blog I wrote on the subject, this will show you exactly how to get you favourite classics working on your PC....
No, you cannot !Directly from the Sega Saturn manual:"You cannot use Genesis, Sega CD, or Genesis 32X games or peripheral equipment with your Sega Saturn."