How do you pronounce quelque chose?

Answer 1

It is approximately like "kel-kuh shows." However the "o" of "chose" is not quite like the English "o." More like something in between the "aw" of "Shaw" and the "u" of "club."

Caveat: The "aw" of "Shaw" is different in different dialects of English. If you are fron the American South, your "aw" might sound to Northerners or Englishmen like "ah-oo"--in which case you should not pattern the French vowel after that.