Physiologically, your brain stores memories and bodily function controls as neural pathways (in a number of redundant locations), an overlay of chemical receptor patterns in the brain. Mentally, you...
I'll take a stab at it: This seems to mean that it is a high order of knowledge to have a sense of the limits of one's knowledge. Being 'smart' and 'informed' or 'savvy' is great, but being aware of...