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How does ibuprofen work?

In: Medication and Drugs, Ibuprofen, Painkillers, Anti-Inflammatories [Edit categories]

Answer:

Ibuprofen is an NSAID which is believed to work through inhibition of cyclooxygenase (COX), thus inhibiting prostaglandin synthesis. There are at least 2 variations of cyclooxygenase (COX-1 and COX-2), ibuprofen inhibits both COX-1 and COX-2. It appears that its analgesic, antipyretic, and anti-inflammatory activity are achieved principally through COX-2 inhibition; whereas COX-1 inhibition is responsible for its unwanted effects on platelet aggregation and the GI mucosa.

First answer by ID1164633885. Last edit by ID1164633885. Question popularity: 8 [recommend question].

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