By the port, I assume you mean where the airport and cruise docks are located? It's about a 20-30 minute water taxi ride into the mainland of Venice, which is where the Principe Hotel is. You can pay...
It is about a 20-30 minute water taxi ride. You can take an express taxi for double the price, but it only knocks off about five or ten minutes from your ride.
By direct train from Venice Santa Lucia station it is around 25-30 minutes. By car it is about 20 minutes. It's a great place to visit as a day trip from Venice.