212.26 kilometres (131.89 miles)
412.25 kilometres (256.16 miles)
1,050.2 kilometres (652.57 miles)
It is around 250 miles. The route: Take U.S. 220 SOUTH to I-80 WEST. Take I-80 WEST to I-79 SOUTH to PITTSBURGH at EXIT 19A. Take I-79 SOUTH to Pittsburgh. To get to downtown, take I-376 EAST at EXIT...
There are two Hamiltons in PA. The closest would be near Punxsutawney at 72.34 miles and the Hamilton near State College is 217.32 miles.