359.34 kilometres (223.28 miles)
It's approximately 145 km - 1 hour and 45 minutes drive. There is also another route which is 210 long and it will take you 2 hours and 15 minutes. If you don't like driving for so long I suggest you...
36.88 kilometres (22.92 miles)
21.54 Miles or 34.66 Kilometers http://www.mapcrow.info/Distance_between_Padova_IT_and_Venice_IT.html
83.42 kilometres (51.83 miles)