peroxisomes
Enzymes can be denatured if the pH is too acidic or basic, or at very high or low temperatures.
Reduced in rank, dignity, or esteem. Corrupted or depraved. Reduced in quality or value.
yes it can be degraded by some restriction endonuclease which act some where inside the DNA and than can be 2nd position also
Wastes would accumulate in ecosystem .