How is pseudoephedrine made?

Answer:

Pseudoephedrine synthesis

Molecular formula: (1S,2S)-2-methylamino-1-phenylpropan-1-ol,
to be symbolised as C6H5-1CHOH-2C(CH3)-NH-CH3

Nowadays it's made synthethically, not by extraction of Ephaedra grass anymore.
It looks like something using:

First part
:
The fermentation of benzaldehyd by yeast (Candida or Saccharomyces) species growing on dextrose and with 'help' from the enzyme pyruvate decarboxylase.
Benzaldehyd is then transferred into precursor L-phenylacetylcarbinol (L-PAC, officially named: (1S)-1-hydroxy-1-phenyl-propan-2-one)

Second part:
L-PAC is then chemically converted to pseudoephedrine via reductive amination.
This involves the conversion of the carbonyl group to an amine via an intermediate imine. The carbonyl group is at the '-2-' position on the propan part of LPAC.

(More on 'Synthesis of Pseudoephedrine' and 'Reductive Amination' can be found in Related links, just below this answer)
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First answer by ID3477440790. Last edit by JoppeDeQuint. Contributor trust: 170 [recommend contributor recommended]. Question popularity: 41 [recommend question].