How is the shape of an enzyme important to its function?

Answer:
ligand binding, protein interactions, quaternary model formation, active site way opening and blocking depends upon the protein topology, its surface properties including its shape. The proper shape is provided by special arrangement of motifs and domains in the enzymes (proteins). The weak forces intercations of amino acid are also dependent on shape as hydrophobic tend to be inside in a aqueous environment and hydrophilic as well polar outside (on the surface). Hydrogen bonding with water molecules depends upon shape
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