The serum half life for buproprion is 21 hours, or about one day. You should stop feeling it's effects in a few days. However, you should wait two weeks before starting any drugs which interact negatively with buproprion.
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The mean half-life of elimination is 20-40 hours; longer half-lives, up to 65 hours, have occasionally been recorded but in young men the half-lives have been shorter. Mirtazapine is...