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The duration a cortisone injection stays in your system, also known as its **systemic effect**, depends on several factors, including:

  • **Type of Corticosteroid:** Different types of corticosteroids have varying durations of action. Short-acting corticosteroids typically last **24-48 hours**, while intermediate-acting ones can last *2-4 weeks*. Long-acting corticosteroids can have effects lasting *weeks or even months*.

  • **Injection Site:** The location of the injection can influence how long the cortisone stays in your system. Injections into larger joints or areas with slower blood flow may result in a longer duration of action compared to injections in smaller joints or areas with better blood flow.

  • **Dosage:** The amount of cortisone injected also plays a role. Higher doses may have a longer-lasting effect compared to lower doses.

  • **Individual Factors:** Individual factors like metabolism and body composition can also influence how long the cortisone stays in your system.

Here's a general breakdown:

  • **Short-acting corticosteroids:** Up to **48 hours**.

  • **Intermediate-acting corticosteroids:** **2-4 weeks**.

  • **Long-acting corticosteroids:** **Weeks or months**.

However, it's important to note that the **therapeutic effect**, or the period for which the injection alleviates symptoms, can differ from the systemic effect. While the cortisone may be present in your system for a longer duration, the relief from pain or inflammation may not last as long.

It's crucial to consult with your healthcare professional to understand the specific type and dosage of cortisone used in your injection and the expected duration of its effects. They can provide the most accurate information based on your individual circumstances.

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Amiya Samanta

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3w ago
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Wiki User

9y ago

The body produces a natural cortisone that only lasts for a few minutes. Synthetic cortisone stays in the body for about a month after its injected. It is usually given to treat pain and inflammation.

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Wiki User

16y ago

My last cortisone shot was in 10/07 and I am still itching all over, calves cramping, and skin thinning.

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Wiki User

15y ago

Depending upon the person and the doctor, the standard is 6-8 months.

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Q: How long does cortizone injections stay in your system?
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