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The liver is a unique organ. It is the only organ in the body that is able to regenerate... that is completely repair the damage. With most organs, such as the heart, the damaged tissue is replaced with scar, like on the skin. The liver, however, is able to replace damaged tissue with new cells. An extreme example is a patient who suffers an overdose from Tylenol. In this example up to 50 - 60 percent of the liver cells may be killed within 3 - 4 days. However, if no other complications arise, the patient's liver will repair completely, and a liver biopsy after 30 days will appear completely normal with no signs of damage and no scar. However, the long-term complications of liver disease occur when regeneration is either incomplete or prevented by progressive development of scar tissue within the liver. This occurs when the damaging agent such as a virus, a drug, alcohol, etc., continues to attack the liver and prevents complete regeneration. Once scar tissue has developed it is very difficult to reverse that process. Severe scarring of the liver is the condition known as cirrhosis. The development of cirrhosis indicates late stage liver disease and is usually followed by the onset of complications.

http://www.uihealthcare.com/topics/medicaldepartments/internalmedicine/liverdisease/index.html

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15y ago
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13y ago

I have seen many people in the liver intensive care unit come in with "POD" (paracetamol overdose).

Recovery depends on a few things, the amount taken, the fitness level of the person, the liver function, how much support the patient is receiving with regards to their organs.

Recovery can be anywhere from a week to many many months.

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Q: How long do paracetamol stay in system after overdose?
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Does paracetamol really stay in the liver for seven years after being consumed?

No, if it did you would overdose if you took any more. The drug is metabolized by/in the liver.


Can you take diplofenac sodium tablets and paracetamol together?

Yes Diclofenac can be used as an adjuvant treatment with Paracetamol to reduce pain. They can be used together for up to 48 hours, after that it is reccommended that Paracetamol use be discontinued to avoid it building up in your system. For the same reason you also must not exceed one paracetamol tablet in every 4-6 hours and stay within the daily maximum dose of 4g. There are no interactions between the drugs to worry about but confusion can be caused because Diclofenac can be used long term and Paracetamol cannot, and so if someone believed they could take the two together long term, or simply got used to taking the two together by habit, then they would cause a paracetamol overdose.


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