This depends on the means of transportation that you choose. Misawa has its own Japan Railways Station that connects to Shin-Hachinohe, which is a station on the Touhoku Shinkansen Line. Going from...
It would take about 2 hours and 40 minutes by Shinkansen bullet train to Shin-Kobe station in Kobe-city in Hyogo-prefecture from Shinagawa-station in Tokyo-prefecture.