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Yes. Excedrin (all forms of Excedrin) contain acetaminophen (Tylenol). Acetaminophen in large doses can liver damage and even failure. The dosing instructions state 4000mg a day is the limit, with 1000mg being the max per dose. People who take products with acetaminophen daily may have a limit of 3000mg per day before liver damage occurs.

The FDA is now recognizing the concern. They are talking about changing the maximum doses due to the number of deaths from liver failure from acetaminophen products. Many of those deaths are not intentional overdoses.

It is important to read the labels on everything you are taking. You may be taking Excedrin within instructions, but then grab a cold medicine that also contains acetaminophen. You may injure yourself and be prescribed Vicodin or Percocet, and both of those contain acetaminophen. Be careful mixing medications.

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14y ago
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13y ago

You can overdose on anything. Just follow the dosage instructions and you'll be fine.

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11y ago

Excedrin contains a lot of acetaminophen, and you can do irreversible damage to your liver with as few as ten, in some cases causing "drug-induced hepatitis c"

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Q: Can you overdose on excedrin migrane?
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Can you take excedrin migrane for body aches?

Yes, to great effect.


Can you take excedrin migraine while taking Vyvanse?

DON'T DO IT! Technically you can, but Excedrin migrate has caffeine in it, enough that when I took it while on vyvanse, my heart was racing and I could not stop vommitting. If you can drink a bunch of coffee while on vyvanse, you probably won't have an issue with the Excedrin migrane, but be careful when taking too many stimulants at the same time.


Can you take NyQuil with excedrine migrane?

No. You absolutely positively cannot take both NyQuil and Excedrin of any kind together. They both contain high levels of acetaminophen, which, if overdosed on, could hospitalize you. Excedrin also has aspirin. Whether or not you can take them over so many hours apart, however, is a question to ask.


What happens if you OD on migraine medicine?

If you overdose on Excedrin Migraine (if you take more than 4000mg of acetaminophen, or more than 16 tablets in 24hrs), go to the emergency room as soon as possible. Taking more than 4000mg of Acetaminophen (paracetemol in the UK, and the main ingredient in Tylenol) can cause liver damage and possibly liver failure. At the ER, they will test your liver function and may give you an antidote (N-Acetyl-Cysteine). If you receive the antidote within 4 hours of the last ingestion you may be able to ward off significant liver damage. The amount of tablets a 150lb man or woman would need to overdose on the aspirin component of Excedrin is much higher than the acetaminophen. About 40 tablets. The acetaminophen overdose becomes the primary concern, because at 16-20 tablets you may be causing liver damage. Not all the Excedrins have exactly the same amount of ingredients in them. Excedrin Extra Strength and Excedrin Migraine are the same. Excedrin PM and Excedrin Tension Headache have 500mg of acetaminophen per caplet. Make sure you are taking all acetaminophen containing products into account, including things like Nyquil.


Does Excedrin have aspirin in it?

It is a mixture of the active ingredient in Tylenol combined with aspirin and some caffeine. Excedrin Migraine is the only Excedrin with aspirin. It has: 250mg of aspirin, 250mg of acetaminophen, and 65mg caffeine.


What is the cause of migrane headaches?

joe pasqale


Does Excedrin work for back pain?

Yes. There is an Excedrin Back & Body


When will Excedrin be back on the shelf?

For the most up-to-date information on Excedrin's availability, I recommend checking with retailers or Excedrin's official website for announcements regarding restocking and availability. Generally, the timing of when Excedrin will be back on the shelf can vary due to factors like production, distribution, and demand.


Is excedrin migraine back?

Yes, Excedrin Migraine is back on store shelves.


Is excedrin coming back and when?

sorry but excedrin is never coming back to WWE


What do you give my 9yr old for a migrane?

Consult your doctor.


What is ora migrane?

Please refer to silent migraines.