it depends on where your starting fromActually the correct respons would be, it depends on where you're going TO. because the asker stated "From" Vegas... not "TO" Vegas.
228.77 miles (368.17 kilometres)
265 miles going across to I-15 in the INLAND EMPIRE, then taking I-15 NORTH, towards BARSTOW, to Las Vegas.
The shortest driving distance is 265 miles.