1,487.45 miles (2,393.81 kilometres)
From Panama City to Colon City its aprox. 79 kms, or 49.5 miles. Expected driving time is 1 hour.
1,324.43 miles (2,131.46 kilometres)
2,313.84 miles (3,723.76 kilometres)
381 miles taking U.S. 231 SOUTH.