3,662.96 miles (5,894.95 kilometres)
About 23 hours following I-95. I would recommend driving to Savannah, Georgia - a little over half way, and then on to the Keys the following day. Driving 10-11 hours per day is the most you should...
2,724.74 miles (4,385.04 kilometres)
654.1 miles (1,052.66 kilometres)
190 miles